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Liquefaction of the Brain following Stroke Shares a Similar Molecular and Morphological Profile with Atherosclerosis and Mediates Secondary Neurodegeneration in an Osteopontin-Dependent Mechanism

Here we used mouse models of heart and brain ischemia to compare the inflammatory response to ischemia in the heart, a protein rich organ, to the inflammatory response to ischemia in the brain, a lipid rich organ. We report that ischemia-induced inflammation resolves between one and four weeks in th...

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Detalles Bibliográficos
Autores principales: Chung, Amanda G., Frye, Jennifer B., Zbesko, Jacob C., Constantopoulos, Eleni, Hayes, Megan, Figueroa, Anna G., Becktel, Danielle A., Antony Day, W., Konhilas, John P., McKay, Brian S., Nguyen, Thuy-Vi V., Doyle, Kristian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223114/
https://www.ncbi.nlm.nih.gov/pubmed/30417081
http://dx.doi.org/10.1523/ENEURO.0076-18.2018