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Evaluation of methodologies to determine the effect of specific active immunotherapy on VEGF levels in phase I clinical trial patients with advanced solid tumors

Two phase I clinical trials were conducted to evaluate, among other parameters, the humoral response elicited by a vascular endothelial growth factor (VEGF)-based therapeutic vaccine in cancer patients with advanced solid tumors. VEGF reduction was studied using an indirect methodology named as “Pla...

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Detalles Bibliográficos
Autores principales: Sánchez Ramírez, Javier, Bequet-Romero, Mónica, Morera Díaz, Yanelys, Hernández-Bernal, Francisco, de la Torre Santos, Ana, Selman-Housein Bernal, Katty-Hind, Martín Bauta, Yenima, Bermúdez Badell, Cimara H., Limonta Fernández, Miladys, Ayala Avila, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223189/
https://www.ncbi.nlm.nih.gov/pubmed/30426104
http://dx.doi.org/10.1016/j.heliyon.2018.e00906