Suitability of hepatocyte cell lines HepG2, AML12 and THLE-2 for investigation of insulin signalling and hepatokine gene expression

Immortal hepatocyte cell lines are widely used to elucidate insulin-dependent signalling pathways and regulation of hepatic metabolism, although the often tumorigenic origin might not represent the metabolic state of healthy hepatocytes. We aimed to investigate if murine cell line AML12 and human ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Sefried, Stephanie, Häring, Hans-Ulrich, Weigert, Cora, Eckstein, Sabine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223207/
https://www.ncbi.nlm.nih.gov/pubmed/30355754
http://dx.doi.org/10.1098/rsob.180147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223207/
https://www.ncbi.nlm.nih.gov/pubmed/30355754
http://dx.doi.org/10.1098/rsob.180147

Ejemplares similares