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Orlistat-loaded solid SNEDDS for the enhanced solubility, dissolution, and in vivo performance
BACKGROUND: The present study aimed to develop orlistat-loaded solid self-nanoemulsifying drug delivery system preconcentrate (SSP) with the minimum use of lipid excipients for the enhanced solubility, in vitro dissolution, lipase inhibition, and in vivo performance. MATERIALS AND METHODS: In the sc...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223334/ https://www.ncbi.nlm.nih.gov/pubmed/30464461 http://dx.doi.org/10.2147/IJN.S181175 |