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Orlistat-loaded solid SNEDDS for the enhanced solubility, dissolution, and in vivo performance

BACKGROUND: The present study aimed to develop orlistat-loaded solid self-nanoemulsifying drug delivery system preconcentrate (SSP) with the minimum use of lipid excipients for the enhanced solubility, in vitro dissolution, lipase inhibition, and in vivo performance. MATERIALS AND METHODS: In the sc...

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Detalles Bibliográficos
Autores principales: Kim, Dae Hun, Kim, Jae Yeol, Kim, Rae Man, Maharjan, Pooja, Ji, Yu-Geun, Jang, Dong-Jin, Min, Kyoung Ah, Koo, Tae-Sung, Cho, Kwan Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223334/
https://www.ncbi.nlm.nih.gov/pubmed/30464461
http://dx.doi.org/10.2147/IJN.S181175