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Resveratrol, an activator of SIRT1, induces protective autophagy in non-small-cell lung cancer via inhibiting Akt/mTOR and activating p38-MAPK

BACKGROUND: Resveratrol, a natural polyphenolic phytoalexin, has potent anti-tumor activity. Recently, it was found to induce autophagy in cancer cells. However, the effects of resveratrol on autophagy in non-small-cell lung cancer (NSCLC) cells have not yet been clearly elucidated. MATERIALS AND ME...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Li, Jiamei, Cao, Naiqing, Li, Zhen, Han, Jingying, Li, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223384/
https://www.ncbi.nlm.nih.gov/pubmed/30464525
http://dx.doi.org/10.2147/OTT.S159095