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Outcomes in Treatment-Naïve Patients With Metastatic Extremity Osteosarcoma Treated With OGS-12, a Novel Non–High-Dose Methotrexate–Based, Dose-Dense Combination Chemotherapy, in a Tertiary Care Cancer Center

PURPOSE: Metastatic osteosarcoma is largely treated with high-dose methotrexate (HDMTX)–based therapy, especially in the pediatric population. This mandates complex pharmacokinetic monitoring in a costly inpatient setting to mitigate unpredictable serious toxicities. Hence, a non-HDMTX–based regimen...

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Detalles Bibliográficos
Autores principales: Bajpai, Jyoti, Chandrasekharan, Arun, Simha, Vijai, Talreja, Vikas, Karpe, Ashay, Pandey, Nikihil, Singh, Ashish, Rekhi, Bharat, Vora, Tushar, Ghosh, Jaya, Banavali, Shripad, Gupta, Sudeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Clinical Oncology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223433/
https://www.ncbi.nlm.nih.gov/pubmed/30241240
http://dx.doi.org/10.1200/JGO.17.00137