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SAMMSON fosters cancer cell fitness by enhancing concertedly mitochondrial and cytosolic translation

Synchronisation of translation rates between the mitochondria and their cellular host is critical for the maintenance of cellular fitness, with cancer cells being especially vulnerable to translation uncoupling. Although alterations of cytosolic protein synthesis are common in human cancer, the comp...

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Detalles Bibliográficos
Autores principales: Roberto, Vendramin, Yvessa, Verheyden, Hideaki, Ishikawa, Lucas, Goedert, Emilien, Nicolas, Kritika, Saraf, Alexandros, Armaos, Riccardo, Delli Ponti, Keiichi, Izumikawa, Pieter, Mestdagh, Denis, Lafontaine L.J., Gaetano, Tartaglia Gian, Nobuhiro, Takahashi, Jean-Christophe, Marine, Eleonora, Leucci
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223542/
https://www.ncbi.nlm.nih.gov/pubmed/30374086
http://dx.doi.org/10.1038/s41594-018-0143-4