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SAMMSON fosters cancer cell fitness by enhancing concertedly mitochondrial and cytosolic translation
Synchronisation of translation rates between the mitochondria and their cellular host is critical for the maintenance of cellular fitness, with cancer cells being especially vulnerable to translation uncoupling. Although alterations of cytosolic protein synthesis are common in human cancer, the comp...
Autores principales: | Roberto, Vendramin, Yvessa, Verheyden, Hideaki, Ishikawa, Lucas, Goedert, Emilien, Nicolas, Kritika, Saraf, Alexandros, Armaos, Riccardo, Delli Ponti, Keiichi, Izumikawa, Pieter, Mestdagh, Denis, Lafontaine L.J., Gaetano, Tartaglia Gian, Nobuhiro, Takahashi, Jean-Christophe, Marine, Eleonora, Leucci |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223542/ https://www.ncbi.nlm.nih.gov/pubmed/30374086 http://dx.doi.org/10.1038/s41594-018-0143-4 |
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