A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose, Multiple Dose, and Food Effect Trial of the Safety, Tolerability and Pharmacokinetics of Highly Purified Cannabidiol in Healthy Subjects

BACKGROUND: A formal single ascending and multiple dose pharmacokinetic (PK) trial of cannabidiol (CBD) oral solution was required to determine the safety and tolerability of CBD, the maximum tolerated dose, and to examine the effect of food on CBD PK parameters. OBJECTIVE: This trial assessed the s...

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Detalles Bibliográficos
Autores principales: Taylor, Lesley, Gidal, Barry, Blakey, Graham, Tayo, Bola, Morrison, Gilmour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223703/
https://www.ncbi.nlm.nih.gov/pubmed/30374683
http://dx.doi.org/10.1007/s40263-018-0578-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223703/
https://www.ncbi.nlm.nih.gov/pubmed/30374683
http://dx.doi.org/10.1007/s40263-018-0578-5

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