Generation of Cas9 transgenic zebrafish and their application in establishing an ERV-deficient animal model

OBJECTIVES: To investigate the effect of endogenous Cas9 on genome editing efficiency in transgenic zebrafish. RESULTS: Here we have constructed a transgenic zebrafish strain that can be screened by pigment deficiency. Compared with the traditional CRISPR injection method, the transgenic zebrafish c...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Zhe, Chen, Shihao, Xue, Songlei, Li, Xinxiu, Sun, Zhen, Yang, Yu, Hu, Xuming, Geng, Tuoyu, Cui, Hengmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2018
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223727/
https://www.ncbi.nlm.nih.gov/pubmed/30244429
http://dx.doi.org/10.1007/s10529-018-2605-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223727/
https://www.ncbi.nlm.nih.gov/pubmed/30244429
http://dx.doi.org/10.1007/s10529-018-2605-5

Ejemplares similares