Overexpression of modified human TRβ1 suppresses the growth of hepatocarcinoma SK-hep1 cells in vitro and in xenograft models

Association studies suggest that TRβ1 functions as a tumor suppressor. Thyroid hormone receptors (TRs) mediate transcriptional responses through a highly conserved DNA-binding domain (DBD). We previously constructed an artificially modified human TRβ1 (m-TRβ1) via the introduction of a 108-bp exon s...

Descripción completa

Detalles Bibliográficos
Autores principales: Peng, Xiaoxiang, Zhou, Yuntao, Sun, Yanli, Song, Wei, Meng, Xiangying, Zhao, Chunling, Zhao, Ronglan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223806/
https://www.ncbi.nlm.nih.gov/pubmed/29679278
http://dx.doi.org/10.1007/s11010-018-3357-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223806/
https://www.ncbi.nlm.nih.gov/pubmed/29679278
http://dx.doi.org/10.1007/s11010-018-3357-1

Ejemplares similares