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Overexpression of modified human TRβ1 suppresses the growth of hepatocarcinoma SK-hep1 cells in vitro and in xenograft models

Association studies suggest that TRβ1 functions as a tumor suppressor. Thyroid hormone receptors (TRs) mediate transcriptional responses through a highly conserved DNA-binding domain (DBD). We previously constructed an artificially modified human TRβ1 (m-TRβ1) via the introduction of a 108-bp exon s...

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Detalles Bibliográficos
Autores principales:	Peng, Xiaoxiang, Zhou, Yuntao, Sun, Yanli, Song, Wei, Meng, Xiangying, Zhao, Chunling, Zhao, Ronglan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223806/ https://www.ncbi.nlm.nih.gov/pubmed/29679278 http://dx.doi.org/10.1007/s11010-018-3357-1

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