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Elucidating the Uptake and Distribution of Nanoparticles in Solid Tumors via a Multilayered Cell Culture Model

Multicellular layers (MCLs) have previously been used to determine the pharmacokinetics of a variety of different cancer drugs including paclitaxel, doxorubicin, methotrexate, and 5-fluorouracil across a number of cell lines. It is not known how nanoparticles (NPs) navigate through the tumor microen...

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Detalles Bibliográficos
Autores principales: Yohan, Darren, Cruje, Charmainne, Lu, Xiaofeng, Chithrani, Devika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223939/
https://www.ncbi.nlm.nih.gov/pubmed/30464963
http://dx.doi.org/10.1007/s40820-014-0025-1