Enhancement by Nano-Diamino-Tetrac of Antiproliferative Action of Gefitinib on Colorectal Cancer Cells: Mediation by EGFR Sialylation and PI3K Activation

Drug resistance complicates the clinical use of gefitinib. Tetraiodothyroacetic acid (tetrac) and nano-diamino-tetrac (NDAT) have been shown in vitro and in xenografts to have antiproliferative/angiogenic properties and to potentiate antiproliferative activity of other anticancer agents. In the curr...

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Detalles Bibliográficos
Autores principales: Chang, Tung-Cheng, Chin, Yu-Tang, Nana, André Wendindondé, Wang, Shwu-Huey, Liao, Yu-Min, Chen, Yi-Ru, Shih, Ya-Jung, Changou, Chun A., Yang, Yu-Chen SH, Wang, Kuan, Whang-Peng, Jacqueline, Wang, Liang-Shun, Stain, Steven C., Shih, Ai, Lin, Hung-Yun, Wu, Chih-Hsiung, Davis, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223990/
https://www.ncbi.nlm.nih.gov/pubmed/30187356
http://dx.doi.org/10.1007/s12672-018-0341-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223990/
https://www.ncbi.nlm.nih.gov/pubmed/30187356
http://dx.doi.org/10.1007/s12672-018-0341-x

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