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Enhancement by Nano-Diamino-Tetrac of Antiproliferative Action of Gefitinib on Colorectal Cancer Cells: Mediation by EGFR Sialylation and PI3K Activation
Drug resistance complicates the clinical use of gefitinib. Tetraiodothyroacetic acid (tetrac) and nano-diamino-tetrac (NDAT) have been shown in vitro and in xenografts to have antiproliferative/angiogenic properties and to potentiate antiproliferative activity of other anticancer agents. In the curr...
Autores principales: | Chang, Tung-Cheng, Chin, Yu-Tang, Nana, André Wendindondé, Wang, Shwu-Huey, Liao, Yu-Min, Chen, Yi-Ru, Shih, Ya-Jung, Changou, Chun A., Yang, Yu-Chen SH, Wang, Kuan, Whang-Peng, Jacqueline, Wang, Liang-Shun, Stain, Steven C., Shih, Ai, Lin, Hung-Yun, Wu, Chih-Hsiung, Davis, Paul J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223990/ https://www.ncbi.nlm.nih.gov/pubmed/30187356 http://dx.doi.org/10.1007/s12672-018-0341-x |
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