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Mitochondrial pathophysiology beyond the retinal ganglion cell: occipital GABA is decreased in autosomal dominant optic neuropathy

PURPOSE: It has remained a mystery why some genetic mitochondrial disorders affect predominantly specific cell types such as the retinal ganglion cell. This is particularly intriguing concerning retinal and cortical function since they are tightly linked in health and disease. Autosomal dominant opt...

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Detalles Bibliográficos
Autores principales: d’Almeida, Otília C., Violante, Inês R., Quendera, Bruno, Castelo-Branco, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224020/
https://www.ncbi.nlm.nih.gov/pubmed/30324419
http://dx.doi.org/10.1007/s00417-018-4153-z