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Systematically benchmarking peptide-MHC binding predictors: From synthetic to naturally processed epitopes

A number of machine learning-based predictors have been developed for identifying immunogenic T-cell epitopes based on major histocompatibility complex (MHC) class I and II binding affinities. Rationally selecting the most appropriate tool has been complicated by the evolving training data and machi...

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Detalles Bibliográficos
Autores principales: Zhao, Weilong, Sher, Xinwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224037/
https://www.ncbi.nlm.nih.gov/pubmed/30408041
http://dx.doi.org/10.1371/journal.pcbi.1006457