Role of variant allele fraction and rare SNP filtering to improve cellular DNA repair endpoint association

BACKGROUND: Large cancer genome studies continue to reveal new players in treatment response and tumorigenesis. The discrimination of functional alterations from the abundance of passenger genetic alterations still poses challenges and determines DNA sequence variant selection procedures. Here we ev...

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Detalles Bibliográficos
Autores principales: Vossen, David M., Verhagen, Caroline V. M., Grénman, Reidar, Kluin, Roelof J. C., Verheij, Marcel, van den Brekel, Michiel W. M., Wessels, Lodewyk F. A., Vens, Conchita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224072/
https://www.ncbi.nlm.nih.gov/pubmed/30408064
http://dx.doi.org/10.1371/journal.pone.0206632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224072/
https://www.ncbi.nlm.nih.gov/pubmed/30408064
http://dx.doi.org/10.1371/journal.pone.0206632

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