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Role of variant allele fraction and rare SNP filtering to improve cellular DNA repair endpoint association
BACKGROUND: Large cancer genome studies continue to reveal new players in treatment response and tumorigenesis. The discrimination of functional alterations from the abundance of passenger genetic alterations still poses challenges and determines DNA sequence variant selection procedures. Here we ev...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224072/ https://www.ncbi.nlm.nih.gov/pubmed/30408064 http://dx.doi.org/10.1371/journal.pone.0206632 |