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A Tuba/Cdc42/Par6A complex is required to ensure singularity in apical domain formation during enterocyte polarization

Apico-basal polarity establishment is a seminal process in tissue morphogenesis. To function properly it is often imperative that epithelial cells limit apical membrane formation to a single domain. We previously demonstrated that signaling by the small GTPase Cdc42, together with its guanine nucleo...

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Detalles Bibliográficos
Autores principales: Bruurs, Lucas J. M., van der Net, Mirjam C., Zwakenberg, Susan, Zwartkruis, Fried J. T., Bos, Johannes L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224091/
https://www.ncbi.nlm.nih.gov/pubmed/30408122
http://dx.doi.org/10.1371/journal.pone.0207159