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Computational discovery of dynamic cell line specific Boolean networks from multiplex time-course data

Protein signaling networks are static views of dynamic processes where proteins go through many biochemical modifications such as ubiquitination and phosphorylation to propagate signals that regulate cells and can act as feed-back systems. Understanding the precise mechanisms underlying protein inte...

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Detalles Bibliográficos
Autores principales: Razzaq, Misbah, Paulevé, Loïc, Siegel, Anne, Saez-Rodriguez, Julio, Bourdon, Jérémie, Guziolowski, Carito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224120/
https://www.ncbi.nlm.nih.gov/pubmed/30372442
http://dx.doi.org/10.1371/journal.pcbi.1006538