Loss of CXCL12/CXCR4 signalling impacts several aspects of cardiovascular development but does not exacerbate Tbx1 haploinsufficiency

The CXCL12-CXCR4 pathway has crucial roles in stem cell homing and maintenance, neuronal guidance, cancer progression, inflammation, remote-conditioning, cell migration and development. Recently, work in chick suggested that signalling via CXCR4 in neural crest cells (NCCs) has a role in the 22q11.2...

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Detalles Bibliográficos
Autores principales: Page, Mahalia, Ridge, Liam, Gold Diaz, Diana, Tsogbayar, Tsolmon, Scambler, Peter J., Ivins, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224166/
https://www.ncbi.nlm.nih.gov/pubmed/30408103
http://dx.doi.org/10.1371/journal.pone.0207251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224166/
https://www.ncbi.nlm.nih.gov/pubmed/30408103
http://dx.doi.org/10.1371/journal.pone.0207251

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