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CD4 T cells control development and maintenance of brain-resident CD8 T cells during polyomavirus infection

Tissue-resident memory CD8 T (T(RM)) cells defend against microbial reinfections at mucosal barriers; determinants driving durable T(RM) cell responses in non-mucosal tissues, which often harbor opportunistic persistent pathogens, are unknown. JC polyomavirus (JCPyV) is a ubiquitous constituent of t...

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Detalles Bibliográficos
Autores principales: Mockus, Taryn E., Shwetank, Lauver, Matthew D., Ren, Heather M., Netherby, Colleen S., Salameh, Tarik, Kawasawa, Yuka Imamura, Yue, Feng, Broach, James R., Lukacher, Aron E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224182/
https://www.ncbi.nlm.nih.gov/pubmed/30372487
http://dx.doi.org/10.1371/journal.ppat.1007365