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Feedback regulation of cytoneme-mediated transport shapes a tissue-specific FGF morphogen gradient
Gradients of signaling proteins are essential for inducing tissue morphogenesis. However, mechanisms of gradient formation remain controversial. Here we characterized the distribution of fluorescently-tagged signaling proteins, FGF and FGFR, expressed at physiological levels from the genomic knock-i...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224196/ https://www.ncbi.nlm.nih.gov/pubmed/30328809 http://dx.doi.org/10.7554/eLife.38137 |