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Feedback regulation of cytoneme-mediated transport shapes a tissue-specific FGF morphogen gradient

Gradients of signaling proteins are essential for inducing tissue morphogenesis. However, mechanisms of gradient formation remain controversial. Here we characterized the distribution of fluorescently-tagged signaling proteins, FGF and FGFR, expressed at physiological levels from the genomic knock-i...

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Detalles Bibliográficos
Autores principales: Du, Lijuan, Sohr, Alex, Yan, Ge, Roy, Sougata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224196/
https://www.ncbi.nlm.nih.gov/pubmed/30328809
http://dx.doi.org/10.7554/eLife.38137