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Host-cell DNA methylation patterns during high-risk HPV-induced carcinogenesis reveal a heterogeneous nature of cervical pre-cancer

Cervical cancer development following a persistent infection with high-risk human papillomavirus (hrHPV) is driven by additional host-cell changes, such as altered DNA methylation. In previous studies, we have identified 12 methylated host genes associated with cervical cancer and pre-cancer (CIN2/3...

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Detalles Bibliográficos
Autores principales: Verlaat, Wina, Van Leeuwen, Robert W., Novianti, Putri W., Schuuring, Ed, Meijer, Chris J. L. M., Van Der Zee, Ate G. J., Snijders, Peter J. F., Heideman, Daniëlle A. M., Steenbergen, Renske D. M., Wisman, G. Bea A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224221/
https://www.ncbi.nlm.nih.gov/pubmed/30079796
http://dx.doi.org/10.1080/15592294.2018.1507197