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The mitomiR/Bcl-2 axis affects mitochondrial function and autophagic vacuole formation in senescent endothelial cells

During senescence, cells undergo distinctive biochemical and morphological changes and become dysfunctional. MiRNAs are involved in the senescence process and specific miRNAs can localize to mitochondria (mitomiRs). We hypothesized that part of the typical alterations of senescence may depends on mi...

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Detalles Bibliográficos
Autores principales: Giuliani, Angelica, Cirilli, Ilenia, Prattichizzo, Francesco, Mensà, Emanuela, Fulgenzi, Gianluca, Sabbatinelli, Jacopo, Graciotti, Laura, Olivieri, Fabiola, Procopio, Antonio Domenico, Tiano, Luca, Rippo, Maria Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224225/
https://www.ncbi.nlm.nih.gov/pubmed/30348904
http://dx.doi.org/10.18632/aging.101591