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The mitomiR/Bcl-2 axis affects mitochondrial function and autophagic vacuole formation in senescent endothelial cells
During senescence, cells undergo distinctive biochemical and morphological changes and become dysfunctional. MiRNAs are involved in the senescence process and specific miRNAs can localize to mitochondria (mitomiRs). We hypothesized that part of the typical alterations of senescence may depends on mi...
Autores principales: | Giuliani, Angelica, Cirilli, Ilenia, Prattichizzo, Francesco, Mensà, Emanuela, Fulgenzi, Gianluca, Sabbatinelli, Jacopo, Graciotti, Laura, Olivieri, Fabiola, Procopio, Antonio Domenico, Tiano, Luca, Rippo, Maria Rita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224225/ https://www.ncbi.nlm.nih.gov/pubmed/30348904 http://dx.doi.org/10.18632/aging.101591 |
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