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Sirtuin 3 attenuates amyloid-β induced neuronal hypometabolism

Alzheimer’s disease (AD) is manifested by regional cerebral hypometabolism. Sirtuin 3 (Sirt3) is localized in mitochondria and regulates cellular metabolism, but the role of Sirt3 in AD-related hypometabolism remains elusive. We used expression profiling and weighted gene co-expression network analy...

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Detalles Bibliográficos
Autores principales: Yin, Junxiang, Li, Shiping, Nielsen, Megan, Carcione, Tanner, Liang, Winnie S., Shi, Jiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224231/
https://www.ncbi.nlm.nih.gov/pubmed/30362958
http://dx.doi.org/10.18632/aging.101592