H3K9me3 and H4K20me3 represent the epigenetic landscape for 53BP1 binding to DNA lesions

Methylation of histones H4 at lysine 20 position (H4K20me), which is functional in DNA repair, represents a binding site for the 53BP1 protein. Here, we show a radiation-induced increase in the level of H4K20me3 while the levels of H4K20me1 and H4K20me2 remained intact. H4K20me3 was significantly pr...

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Detalles Bibliográficos
Autores principales: Svobodová Kovaříková, Alena, Legartová, Soňa, Krejčí, Jana, Bartová, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224238/
https://www.ncbi.nlm.nih.gov/pubmed/30312172
http://dx.doi.org/10.18632/aging.101572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224238/
https://www.ncbi.nlm.nih.gov/pubmed/30312172
http://dx.doi.org/10.18632/aging.101572

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