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H3K9me3 and H4K20me3 represent the epigenetic landscape for 53BP1 binding to DNA lesions
Methylation of histones H4 at lysine 20 position (H4K20me), which is functional in DNA repair, represents a binding site for the 53BP1 protein. Here, we show a radiation-induced increase in the level of H4K20me3 while the levels of H4K20me1 and H4K20me2 remained intact. H4K20me3 was significantly pr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224238/ https://www.ncbi.nlm.nih.gov/pubmed/30312172 http://dx.doi.org/10.18632/aging.101572 |