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Melatonin prevents senescence of canine adipose-derived mesenchymal stem cells through activating NRF2 and inhibiting ER stress

Transplantation of adipose-derived mesenchymal stem cells (ADMSCs) can aid in the treatment of numerous diseases in animals. However, natural aging during in vitro expansion of ADMSCs prior to their use in transplantation restricts their beneficial effects. Melatonin is reported to exert biorhythm r...

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Detalles Bibliográficos
Autores principales: Fang, Jia, Yan, Yuan, Teng, Xin, Wen, Xinyu, Li, Na, Peng, Sha, Liu, Wenshuai, Donadeu, F. Xavier, Zhao, Shanting, Hua, Jinlian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224246/
https://www.ncbi.nlm.nih.gov/pubmed/30362962
http://dx.doi.org/10.18632/aging.101602