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Melatonin prevents senescence of canine adipose-derived mesenchymal stem cells through activating NRF2 and inhibiting ER stress
Transplantation of adipose-derived mesenchymal stem cells (ADMSCs) can aid in the treatment of numerous diseases in animals. However, natural aging during in vitro expansion of ADMSCs prior to their use in transplantation restricts their beneficial effects. Melatonin is reported to exert biorhythm r...
Autores principales: | Fang, Jia, Yan, Yuan, Teng, Xin, Wen, Xinyu, Li, Na, Peng, Sha, Liu, Wenshuai, Donadeu, F. Xavier, Zhao, Shanting, Hua, Jinlian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224246/ https://www.ncbi.nlm.nih.gov/pubmed/30362962 http://dx.doi.org/10.18632/aging.101602 |
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