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Nuclear Nox4 interaction with prelamin A is associated with nuclear redox control of stem cell aging

Mesenchymal stem cells have emerged as an important tool that can be used for tissue regeneration thanks to their easy preparation, differentiation potential and immunomodulatory activity. However, an extensive culture of stem cells in vitro prior to clinical use can lead to oxidative stress that ca...

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Detalles Bibliográficos
Autores principales: Casciaro, Francesca, Beretti, Francesca, Zavatti, Manuela, McCubrey, James A., Ratti, Stefano, Marmiroli, Sandra, Follo, Matilde Y., Maraldi, Tullia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224265/
https://www.ncbi.nlm.nih.gov/pubmed/30362963
http://dx.doi.org/10.18632/aging.101599