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Inhibition of mTORC2/RICTOR Impairs Melanoma Hepatic Metastasis()()
Mammalian target of rapamycin complex 2 (mTORC2) with its pivotal component rapamycin-insensitive companion of mTOR (RICTOR) is the major regulator of AKT phosphorylation and is increasingly implicated in tumor growth and progression. In cutaneous melanoma, an extremely aggressive and highly metasta...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224335/ https://www.ncbi.nlm.nih.gov/pubmed/30404068 http://dx.doi.org/10.1016/j.neo.2018.10.001 |