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Inhibition of mTORC2/RICTOR Impairs Melanoma Hepatic Metastasis()()

Mammalian target of rapamycin complex 2 (mTORC2) with its pivotal component rapamycin-insensitive companion of mTOR (RICTOR) is the major regulator of AKT phosphorylation and is increasingly implicated in tumor growth and progression. In cutaneous melanoma, an extremely aggressive and highly metasta...

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Detalles Bibliográficos
Autores principales:	Schmidt, Katharina M., Dietrich, Peter, Hackl, Christina, Guenzle, Jessica, Bronsert, Peter, Wagner, Christine, Fichtner-Feigl, Stefan, Schlitt, Hans J., Geissler, Edward K., Hellerbrand, Claus, Lang, Sven A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2018
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224335/ https://www.ncbi.nlm.nih.gov/pubmed/30404068 http://dx.doi.org/10.1016/j.neo.2018.10.001

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