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The Emerging Role of Lamin C as an Important LMNA Isoform in Mechanophenotype

Lamin A and lamin C isoforms of the gene LMNA are major structural and mechanotransductive components of the nuclear lamina. Previous reports have proposed lamin A as the isoform with the most dominant contributions to cellular mechanophenotype. Recently, expression of lamin C has also been shown to...

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Detalles Bibliográficos
Autores principales: González-Cruz, Rafael D., Dahl, Kris N., Darling, Eric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224339/
https://www.ncbi.nlm.nih.gov/pubmed/30450357
http://dx.doi.org/10.3389/fcell.2018.00151