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Regenerative Approaches in Huntington’s Disease: From Mechanistic Insights to Therapeutic Protocols

Huntington’s Disease (HD) is a neurodegenerative disorder caused by a CAG expansion in the exon-1 of the IT15 gene encoding the protein Huntingtin. Expression of mutated Huntingtin in humans leads to dysfunction and ultimately degeneration of selected neuronal populations of the striatum and cerebra...

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Detalles Bibliográficos
Autores principales:	Sassone, Jenny, Papadimitriou, Elsa, Thomaidou, Dimitra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224350/ https://www.ncbi.nlm.nih.gov/pubmed/30450032 http://dx.doi.org/10.3389/fnins.2018.00800

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