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Calcium-Mediated Oscillation in Membrane Potentials and Atrial-Triggered Activity in Atrial Cells of Casq2(R33Q/R33Q) Mutation Mice

Aim: We investigated the underlying mechanisms in atrial fibrillation (AF) associated with R33Q mutation and Ca(2+)-triggered activity. Methods and Results: We examined AF susceptibility with intraesophageal burst pacing in the sarcoplasmic reticulum (SR) Ca(2+) leak model calsequestrin 2 R33Q (Casq...

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Detalles Bibliográficos
Autores principales: Zhang, Jian-cheng, Wu, Hong-lin, Chen, Qian, Xie, Xiao-ting, Zou, Tian, Zhu, Chao, Dong, Ying, Xiang, Guo-jian, Ye, Lei, Li, Yang, Zhu, Peng-li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224359/
https://www.ncbi.nlm.nih.gov/pubmed/30450052
http://dx.doi.org/10.3389/fphys.2018.01447