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Risk stratification of cervical disease using detection of human papillomavirus (HPV) E4 protein and cellular MCM protein in clinical liquid based cytology samples

BACKGROUND: While human papillomavirus (HPV) DNA testing offers high sensitivity for the detection of significant cervical disease, its specificity is suboptimal given the high prevalence of transient HPV infections (CIN1 or less). Biomarkers to identify those suffering from low grade disease from t...

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Detalles Bibliográficos
Autores principales: Stevenson, Andrew, Kavanagh, Kim, Pan, Jiafeng, Stevenson, Lynne, Griffin, Heather, Doorbar, John, Scott, Evelyn, Deeny, Miriam, Cuschieri, Kate, Graham, Sheila V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224362/
https://www.ncbi.nlm.nih.gov/pubmed/30218891
http://dx.doi.org/10.1016/j.jcv.2018.08.011