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Both Type I and Type II Interferons Can Activate Antitumor M1 Macrophages When Combined With TLR Stimulation

Triggering or enhancing antitumor activity of tumor-associated macrophages is an attractive strategy for cancer treatment. We have previously shown that the cytokine interferon-γ (IFN-γ), a type II IFN, could synergize with toll-like receptor (TLR) agonists for induction of antitumor M1 macrophages....

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Detalles Bibliográficos
Autores principales: Müller, Elisabeth, Speth, Martin, Christopoulos, Panagiotis F., Lunde, Anna, Avdagic, Ajna, Øynebråten, Inger, Corthay, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224375/
https://www.ncbi.nlm.nih.gov/pubmed/30450098
http://dx.doi.org/10.3389/fimmu.2018.02520