Convergence of independent DISC1 mutations on impaired neurite growth via decreased UNC5D expression

The identification of convergent phenotypes in different models of psychiatric illness highlights robust phenotypes that are more likely to be implicated in disease pathophysiology. Here, we utilize human iPSCs harboring distinct mutations in DISC1 that have been found in families with major mental...

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Detalles Bibliográficos
Autores principales: Srikanth, Priya, Lagomarsino, Valentina N., Pearse, Richard V., Liao, Meichen, Ghosh, Sulagna, Nehme, Ralda, Seyfried, Nicholas, Eggan, Kevin, Young-Pearse, Tracy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224395/
https://www.ncbi.nlm.nih.gov/pubmed/30410030
http://dx.doi.org/10.1038/s41398-018-0281-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224395/
https://www.ncbi.nlm.nih.gov/pubmed/30410030
http://dx.doi.org/10.1038/s41398-018-0281-9

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