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Convergence of independent DISC1 mutations on impaired neurite growth via decreased UNC5D expression
The identification of convergent phenotypes in different models of psychiatric illness highlights robust phenotypes that are more likely to be implicated in disease pathophysiology. Here, we utilize human iPSCs harboring distinct mutations in DISC1 that have been found in families with major mental...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224395/ https://www.ncbi.nlm.nih.gov/pubmed/30410030 http://dx.doi.org/10.1038/s41398-018-0281-9 |