Whole-genome sequencing of multiple myeloma reveals oncogenic pathways are targeted somatically through multiple mechanisms

Multiple myeloma (MM) is a biologically heterogeneous malignancy, however, the mechanisms underlying this complexity are incompletely understood. We report an analysis of the whole-genome sequencing of 765 MM patients from CoMMpass. By employing promoter capture Hi-C in naïve B-cells, we identify ci...

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Detalles Bibliográficos
Autores principales: Hoang, Phuc H., Dobbins, Sara E., Cornish, Alex J., Chubb, Daniel, Law, Philip J., Kaiser, Martin, Houlston, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224406/
https://www.ncbi.nlm.nih.gov/pubmed/29654271
http://dx.doi.org/10.1038/s41375-018-0103-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224406/
https://www.ncbi.nlm.nih.gov/pubmed/29654271
http://dx.doi.org/10.1038/s41375-018-0103-3

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