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Inducing controlled cell cycle arrest and re-entry during asexual proliferation of Plasmodium falciparum malaria parasites

The life cycle of the malaria parasite Plasmodium falciparum is tightly regulated, oscillating between stages of intense proliferation and quiescence. Cyclic 48-hour asexual replication of Plasmodium is markedly different from cell division in higher eukaryotes, and mechanistically poorly understood...

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Detalles Bibliográficos
Autores principales: van Biljon, Riëtte, Niemand, Jandeli, van Wyk, Roelof, Clark, Katherine, Verlinden, Bianca, Abrie, Clarissa, von Grüning, Hilde, Smidt, Werner, Smit, Annél, Reader, Janette, Painter, Heather, Llinás, Manuel, Doerig, Christian, Birkholtz, Lyn-Marié
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224408/
https://www.ncbi.nlm.nih.gov/pubmed/30409996
http://dx.doi.org/10.1038/s41598-018-34964-w