Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family

Iron(II)/α-ketoacid-dependent oxygenases (αKAOs) are enzymes that catalyze the oxidation of unactivated C-H bonds, mainly through hydroxylation. Among these, those that are active towards amino-acids and their derivatives are grouped in the Clavaminate Synthase Like (CSL) family. CSL enzymes exhibit...

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Detalles Bibliográficos
Autores principales: Bastard, Karine, Isabet, Tatiana, Stura, Enrico A., Legrand, Pierre, Zaparucha, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224419/
https://www.ncbi.nlm.nih.gov/pubmed/30410048
http://dx.doi.org/10.1038/s41598-018-34795-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224419/
https://www.ncbi.nlm.nih.gov/pubmed/30410048
http://dx.doi.org/10.1038/s41598-018-34795-9

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