Combined Metabolic Targeting With Metformin and the NSAIDs Diflunisal and Diclofenac Induces Apoptosis in Acute Myeloid Leukemia Cells

The accelerated metabolism of tumor cells, inevitable for maintaining high proliferation rates, is an emerging target for tumor therapy. Increased glucose and lipid metabolism as well as mitochondrial activity have been shown in solid tumors but also in leukemic cells. As tumor cells are able to esc...

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Detalles Bibliográficos
Autores principales: Renner, Kathrin, Seilbeck, Anton, Kauer, Nathalie, Ugele, Ines, Siska, Peter J., Brummer, Christina, Bruss, Christina, Decking, Sonja-Maria, Fante, Matthias, Schmidt, Astrid, Hammon, Kathrin, Singer, Katrin, Klobuch, Sebastian, Thomas, Simone, Gottfried, Eva, Peter, Katrin, Kreutz, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224440/
https://www.ncbi.nlm.nih.gov/pubmed/30450049
http://dx.doi.org/10.3389/fphar.2018.01258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224440/
https://www.ncbi.nlm.nih.gov/pubmed/30450049
http://dx.doi.org/10.3389/fphar.2018.01258

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