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Loss of Smad7 Promotes Inflammation in Rheumatoid Arthritis

Objective: Smad7 is an inhibitory Smad and plays a protective role in many inflammatory diseases. However, the roles of Smad7 in rheumatoid arthritis (RA) remain unexplored, which were investigated in this study. Methods: The activation of TGF-β/Smad signaling was examined in synovial tissues of pat...

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Detalles Bibliográficos
Autores principales: Zhou, Gengmin, Sun, Xiaolin, Qin, Qingxia, Lv, Jiyang, Cai, Yueming, Wang, Meiying, Mu, Rong, Lan, Hui-yao, Wang, Qing-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224447/
https://www.ncbi.nlm.nih.gov/pubmed/30450102
http://dx.doi.org/10.3389/fimmu.2018.02537