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Targeted p53 on Small-Molecules-Induced Ferroptosis in Cancers

Ferroptosis is a type of programmed cell death characterized by the accumulation of lipid reactive oxygen species (L-ROS) driven by the oxidative degeneration of lipids in an iron-dependent manner. The mechanism by which lipid oxidative degradation drives ROS-ferroptosis involves metabolic dysfuncti...

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Detalles Bibliográficos
Autores principales: Zhang, Weifen, Gai, Chengcheng, Ding, Dejun, Wang, Fang, Li, Wentong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224449/
https://www.ncbi.nlm.nih.gov/pubmed/30450337
http://dx.doi.org/10.3389/fonc.2018.00507