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CA1 Nampt knockdown recapitulates hippocampal cognitive phenotypes in old mice which nicotinamide mononucleotide improves

Cognitive dysfunction is one of the most concerning outcomes in global population aging. However, the mechanisms by which cognitive functions are impaired during aging remain elusive. It has been established that NAD(+) levels are reduced in multiple tissues and organs, including the brain. We found...

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Detalles Bibliográficos
Autores principales: Johnson, Sean, Wozniak, David F., Imai, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224504/
https://www.ncbi.nlm.nih.gov/pubmed/30416740
http://dx.doi.org/10.1038/s41514-018-0029-z