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CA1 Nampt knockdown recapitulates hippocampal cognitive phenotypes in old mice which nicotinamide mononucleotide improves
Cognitive dysfunction is one of the most concerning outcomes in global population aging. However, the mechanisms by which cognitive functions are impaired during aging remain elusive. It has been established that NAD(+) levels are reduced in multiple tissues and organs, including the brain. We found...
Autores principales: | Johnson, Sean, Wozniak, David F., Imai, S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224504/ https://www.ncbi.nlm.nih.gov/pubmed/30416740 http://dx.doi.org/10.1038/s41514-018-0029-z |
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